ZOTAROLIMUS

ZOTAROLIMUS

Stock Code: 3575944
Manufacturer Part No: SML2196-25MG
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£357.96 (exc VAT) per 25MG
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Biochem/physiol Actions


Zotarolimus (ABT-578) is a semi-synthetic rapamycin analog with immunosuppressant and anti-proliferative activity. It binds to the FKBP12 binding protein, which subsequently binds to the mammalian target of rapamycin (mTOR) causing cell cycle arrest in the G1 phase. Zotarolimus was designed to be used for delivery from drug-eluting coronary stents to prevent restenosis.


Zotarolimus is a second generation Drug Eluting Stent (DES).

Colourwhite to beige
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
SolubilityDMSO: 2 mg/mL, clear
Formpowder
Assay≥95% (HPLC)

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