YN1

YN1

Stock Code: 3574279
Manufacturer Part No: SML0947-10MG
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£113.94 (exc VAT) per 10MG
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Biochem/physiol Actions


YN1 is a potent inhibitor of PFKFB3 (6-Phosphfructo-2-kinase/fructose-2,6-bisphosphatase: IC50 = 670 nM). PFKFB3 is over expressed in many cancers, and catalyzes the production of fructose-2,6-bisphosphate, which can potentiate PFK1 activity, enhancing glycolysis in tumor cells. YN1 inhibits glycolysis and proliferation in HeLa cells.


Packaging


10, 50 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyBMZFZTMWBCFKSS-UHFFFAOYSA-N
InChI1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-15-10(13(11)18)5-6-12(17)14(15)19/h1-7,16-17,19H
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: 10 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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