VU0071063

VU0071063

Stock Code: 3574520
Manufacturer Part No: SML1142-25MG
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£566.89 (exc VAT) per 25MG
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Biochem/physiol Actions


VU0071063 is also known as [7-(4-(tert-butyl)benzyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione]. It serves as a major compound for examining?-cell physiology, KATPchannel gating and a new chemical scaffold for evolving enhanced activators with medicinal chemistry.


VU0071063 is a potent activator of Kir6.2/SUR1 KATP channels (EC50 = 10.3 µM). VU0071063 reversibly inhibits glucose-stimulated calcium influx in mouse β-islet cells. The compound VU0071063 has no affect on Kir6.2/SUR2A channels.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyZFZAIHKQJBMYLO-UHFFFAOYSA-N
InChI1S/C18H22N4O2/c1-18(2,3)13-8-6-12(7-9-13)10-22-11-19-15-14(22)16(23)21(5)17(24)20(15)4/h6-9,11H,10H2,1-5H3
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: 10 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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