VR23

VR23

Stock Code: 3575134
Manufacturer Part No: SML1599-5MG
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£156.00 (exc VAT) per 5MG
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Biochem/physiol Actions


Proteasomes are responsible for the cleavage of peptides in an ATP/ubiquitin-dependent manner.


VR23 is a potent inhibitor of proteasome that primary targets β2 of the 20S proteasome catalytic subunit. VR23 selectively induces apoptosis to cancer cells via cyclin E–mediated centrosome amplification. VR23 exhibit little effect on noncancerous cells.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
SolubilityDMSO: 20 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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