TLQP-21 peptide is involved in the central and peripheral nervous system activities such as regulating reproductive and circadian behaviors, feeding, and body weight. It is also involved in regulating neuropathic pain and peripheral adiposity. TLQP-21 plays a role in stimulating the secretion of insulin and prevents apoptosis of pancreatic cells. It also activates the complement C3a receptor-1 (C3aR1) in the brain.
General description
TLQP-21 peptide is a derivative of VGF and is expressed at higher levels in the brain.