TENOFOVIR

TENOFOVIR

Stock Code: 3575393
Manufacturer Part No: SML1795-5MG
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£208.93 (exc VAT) per 5MG
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Biochem/physiol Actions


Tenofovir is a nucleotide analogue reverse transcriptase inhibitor (nRTI) that causes premature termination of DNA transcription. Tenofovir is an antiretroviral used for HIV treatment and prevention.


Tenofovir has a low oral bioavailability. Hence, it is available as a prodrug called tenofovir disoproxil fumarate. Once ingested, tenofovir disoproxil fumarate is hydrolyzed to tenofovir and phosphorylated. This is then incorporated into the viral DNA which leads to chain termination. Tenofovir is also effective against hepatitis B virus.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keySGOIRFVFHAKUTI-ZCFIWIBFSA-N
InChI1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/t6-/m1/s1
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥98% (HPLC)

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