TCN-201, >=98% (HPLC)

TCN-201, >=98% (HPLC)

Stock Code: 3574072
Manufacturer Part No: SML0416-25MG
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£463.82 (exc VAT) per 25MG
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Biochem/physiol Actions


TCN-201 is the first NMDA receptor antagonist that is specific for NR2A-subunit containing receptors. The pIC50 for NR2A NMDA receptors is 6.8. TCN-201has no effect on NR2B-containing receptors at concentrations up to 50 mM.


TCN-201 is a sulphonamide derivative, that negatively modulates glycine binding to the GluN1 (glutamate receptor subunit) subunit of the receptor.


Features and Benefits


This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyFYIBXBFDXNPBSF-UHFFFAOYSA-N
InChI1S/C21H17ClFN3O4S/c22-18-12-17(10-11-19(18)23)31(29,30)24-13-14-6-8-16(9-7-14)21(28)26-25-20(27)15-4-2-1-3-5-15/h1-12,24H,13H2,(H,25,27)(H,26,28)
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: 5 mg/mL (clear solution)
Formpowder
Assay≥98% (HPLC)

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