TC-2153

TC-2153

Stock Code: 3574722
Manufacturer Part No: SML1299-5MG
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£168.54 (exc VAT) per 5MG
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Biochem/physiol Actions


TC-2153 is a potent inhibitor of STEP (STriatal-Enriched protein tyrosine Phosphatase) that forms a reversible covalent bond with the catalytic cysteine in STEP. TC-2153 increases tyrosine phosphorylation of STEP substrates ERK1/2, Pyk2, and GluN2B in cell cultures. TC-2153 improves cognitive function in transgenic AD mice.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
SolubilityDMSO: 5 mg/mL, clear
Formpowder
Assay≥95% (HPLC)

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