TAROCIN A1

TAROCIN A1

Stock Code: 3575253
Manufacturer Part No: SML1677-5MG
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£140.68 (exc VAT) per 5MG
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Biochem/physiol Actions


Tarocin A1 is an oxazolidinone which inhibits TarO, the first enzyme in teichoic acid synthesis. Tarocin A1 has an IC50 value of 40 nM in a biochemical TarO assay. Tarocin A does not inhibit bacterial growth alone, and exhibits no cytotoxicity against HeLa cells, but it has potent bactericidal syergism with broad spectrum β-lactams, and may restore the clinical efficacy of existing β-lactam antibiotics.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyXWMRKUPNQVITEC-ZSEKCTLFSA-N
InChI1S/C24H18F6N2O3/c1-13-21(16-8-17(23(25,26)27)10-18(9-16)24(28,29)30)35-22(34)32(13)20(33)7-6-15-12-31-11-14-4-2-3-5-19(14)15/h2-5,8-13,21H,6-7H2,1H3/t13-,21-/m
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: 20 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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