Supercinnamaldehyde, >=98% (HPLC)

Supercinnamaldehyde, >=98% (HPLC)

Stock Code: 3573899
Manufacturer Part No: S3322-25MG
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£838.50 (exc VAT) per 25MG
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Application


Supercinnamaldehyde may be used in transient receptor potential ankyrin 1 (TRPA 1)-mediated cell signaling studies.


Biochem/physiol Actions


Supercinnamaldehyde is a transient receptor potential ankyrin 1 (TRPA1) activator; EC50 = 0.8 µM; derivative of cinnamaldehyde; covalently binds to and activates TRPA1 receptor (expressed in nociceptive neurons) by modifying its cysteine residues. Covalent modification of reactive cysteines within TRPA1 can cause channel activation, rapidly signaling potential tissue damage through the pain pathway.


Caution


Air-sensitive


Packaging


5, 25 mg in glass bottle

Colourfaintly red to very dark red
InChI keyCZKBLHCEDVWPRN-JXMROGBWSA-N
InChI1S/C12H11NO2/c1-8(14)7-10-9-5-3-4-6-11(9)13(2)12(10)15/h3-7H,1-2H3/b10-7+
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
SolubilityDMSO: 10 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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