STF-118804

STF-118804

Stock Code: 3574785
Manufacturer Part No: SML1348-5MG
Order Now for 7 day delivery
£146.25 (exc VAT) per 5MG
Quantity: - +

Biochem/physiol Actions


STF-118804 is a highly specific and potent NAMPT (nicotinamide phosphoribosyl transferase) inhibitor that reduces the viability of most B-ALL cell lines. STF 118804 induces leukemia cell apoptosis including leukemia initiating (stem) cells. STF 118804 improves survival in an orthotopic xenotransplant model of high-risk acute lymphoblastic leukemia.


STF-118804 displays pancreatic ductal adenocarcinoma (PDAC) growth reducing potential in combination with chemotherapeutic drugs.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyDLFCEZOMHBPDGI-UHFFFAOYSA-N
InChI1S/C25H23N3O4S/c1-17-5-11-22(12-6-17)33(30,31)16-23-18(2)32-25(28-23)21-9-7-20(8-10-21)24(29)27-15-19-4-3-13-26-14-19/h3-14H,15-16H2,1-2H3,(H,27,29)
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: 20 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

There are no downloads for this product.