SR 142948A, >=98% (HPLC)

SR 142948A, >=98% (HPLC)

Stock Code: 3573979
Manufacturer Part No: SML0015-5MG
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£220.07 (exc VAT) per 5MG
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Application


SR 142948A was used to study the role of neurotensin signaling in intracellular alkanization and expression of IL-8 in human pancreatic cancer cells.


Biochem/physiol Actions


SR 142948A is a non-peptide Neurotensin receptor antagonist


SR 142948A is a potent neurotensin receptor antagonist that affects the expression of c-Fos and has properties of antipsychotic agent. It blocks hypothermia and analgesia induced by neurotensin. It blocks the increase in the concentration of Ca+2 induced by the activation of phospholipase C in CHO cell model.


Features and Benefits


This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.


This compound is featured on the Neurotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyCUYNEHGBVHUQQW-BVJGGMLGSA-N
InChI1S/C39H51N5O6.ClH/c1-23(2)29-21-26(37(46)43(5)15-9-14-42(3)4)12-13-31(29)44-32(35-33(49-6)10-8-11-34(35)50-7)22-30(41-44)36(45)40-39(38(47)48)27-17-24-16-25(19
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥98% (HPLC)

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