SJ000291942

SJ000291942

Stock Code: 3575801
Manufacturer Part No: SML2087-5MG
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£117.98 (exc VAT) per 5MG
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Biochem/physiol Actions


SJ000291942 is an activator of Bone Morphogenetic Protein (BMP) signaling with an EC50 value ﹤ 1 µM. Bone Morphogenetic Proteins (BMPs) are a group of growth factors and cytokines were originally discovered by their ability to induce the formation of bone and cartilage, but are now considered to constitute a group of pivotal morphogenetic signals, orchestrating tissue architecture throughout the body. SJ000291942 was shown to ventralize zebrafish embryos, activate SMAD1/5/8 phosphorylation, and induce the differentiation of C2C12 myoblasts to osteoblasts in manner consistent with BMP4 activation.

Colourwhite to beige
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
SolubilityDMSO: 2 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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