SITAMAQUINE TOSYLATE

Stock Code: 3575057
Manufacturer Part No: SML1542-5MG
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£138.73 (exc VAT) per 5MG
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Biochem/physiol Actions


Sitamaquine is an orally active 8-aminoquinoline analog that exhibit antiplasmodial and antileishmanial activities. Sitamaquine accumulates in Leishmania parasites. Sitamaquine potently inhibits respiratory chain complex II (succinate dehydrogenase), which leads to an apoptosis-like death of Leishmania parasites.


Sitamaquine is also known as WR-6026. It is used in the treatment of visceral leishmaniasis.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyLOBPWLFCZDGYKW-UHFFFAOYSA-N
InChI1S/C21H33N3O.C7H8O3S/c1-5-24(6-2)14-10-8-7-9-12-22-20-16-18(25-4)15-19-17(3)11-13-23-21(19)20;1-6-2-4-7(5-3-6)11(8,9)10/h11,13,15-16,22H,5-10,12,14H2,1-4H3;2-5
ManufacturerSIGMA-ALDRICH
SolubilityH2O: 15 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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