SB 222200, >=98% (HPLC), solid

Stock Code: 3573912
Manufacturer Part No: S5192-10MG
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£321.75 (exc VAT) per 10MG
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Application


The pharmacodynamics profile of SB 222200 enables its use as a tool to study physiological and pathophysiological roles of NK-3 receptor in CNS-modulated behaviors.


Biochem/physiol Actions


Non-peptide NK3 tachykinin receptor antagonist.


SB 222200 is a 2-phenyl-4-quinolinecarboxamides and a selective, reversible and competitive antagonist of human NK-3 receptor that effectively crosses the blood-brain barrier. It inhibits the NK-3 receptor-induced miosis or pupil constriction in conscious rabbits.1,2


Features and Benefits


This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.


Legal Information


Sold for research purposes under agreement from GlaxoSmithKline


Packaging


10, 50 mg in glass bottle

Colourlight yellow
Quality Level100
InChI keyMQNYRKWJSMQECI-QFIPXVFZSA-N
InChI1S/C26H24N2O/c1-3-22(19-12-6-4-7-13-19)28-26(29)24-18(2)25(20-14-8-5-9-15-20)27-23-17-11-10-16-21(23)24/h4-17,22H,3H2,1-2H3,(H,28,29)/t22-/m0/s1
ManufacturerSIGMA-ALDRICH
Formsolid
Assay≥98% (HPLC)

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