SAG Dihydrochloride

SAG Dihydrochloride

Stock Code: 3574741
Manufacturer Part No: SML1314-1MG
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£151.82 (exc VAT) per 1MG
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Application


Smoothened agonist (SAG) dihydrochloride has been used as a sonic hedgehog (SHH) pathway agonist:to study its effects on mouse hippocampal cellsto determine its effects on the mitochondrial network in zebrafish embryoto study its effects on murine embryonic fibroblasts


Biochem/physiol Actions


SAG is a potent and cell-permeable smoothened (Smo) agonist that activates Hedgehog pathway and counteracts Cyclopamine inhibition of Smo.


Packaging


1, 5 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyVFSUUTYAEQOIMW-YHBQERECSA-N
InChI1S/C28H28ClN3OS/c1-30-22-9-11-23(12-10-22)32(28(33)27-26(29)24-7-2-3-8-25(24)34-27)18-19-5-4-6-21(17-19)20-13-15-31-16-14-20/h2-8,13-17,22-23,30H,9-12,18H2,1H3
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
SolubilityH2O: 20 mg/mL, clear
Formlyophilized solid
Assay≥98% (HPLC)

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