S-(4-Nitrobenzyl)-6-thioinosine, >=98%, solid

Stock Code: 3577843
Manufacturer Part No: N2255-250MG

Order Now for 7 day delivery

Descriptions

Biochem/physiol Actions

Inhibitor of equilibrative nucleoside transporters (ENTs), particularly adenosine transporters, in central nervous system and vascular smooth muscle.

Potent adenosine uptake inhibitor

General description

S-(4-Nitrobenzyl)-6-thioinosine (NBTI) belongs to the family of S⁶-substituted 6-thiopurine nucleosides, which regulate nucleoside transport mechanisms in animals. It acts as a ligand of adenosine transporter. Binding sites for NBTI is located on brain capillaries. It functions as a covalent photoaffinity probe for nucleoside transport.

Packaging

25 mg in glass bottle

100, 250 mg in poly bottle

Specifications

Colour	white
Quality Level	100
mp	187-190 °C (lit.)
InChI key	DYCJFJRCWPVDHY-LSCFUAHRSA-N
InChI	1S/C17H17N5O6S/c23-5-11-13(24)14(25)17(28-11)21-8-20-12-15(21)18-7-19-16(12)29-6-9-1-3-10(4-2-9)22(26)27/h1-4,7-8,11,13-14,17,23-25H,5-6H2/t11-,13-,14-,17-/m1/
Manufacturer	SIGMA-ALDRICH
Form	solid
Assay	≥98%