Rp-8-Bromo-beta-phenyl-1,N2-ethenoguanosine 3,5-cyclic monophosphorothioate sodium salt, >=98% (HPLC

Rp-8-Bromo-beta-phenyl-1,N2-ethenoguanosine 3,5-cyclic monophosphorothioate sodium salt, >=98% (HPLC

Stock Code: 3573287
Manufacturer Part No: B6684-1MG
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£385.82 (exc VAT) per 1MG
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Biochem/physiol Actions


Rp-8-Br-PET-cGMPS is metabolically stable, competitive inhibitor of cGMP-dependent protein kinase G. Inhibits both PKG I (Ki?=?30 nM) and PKG II and blocks cGMP-gated retinal type ion channels (IC50?=?25 micromoles).


Features and Benefits


This compound is featured on the PKA & PKG page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


Legal Information


U.S. Patent 5,625,056, DE Patent 4,217,679.


Packaging


1, 5 mg in glass bottle

Colourwhite to beige
Quality Level100
mp240-300 °C (lit.)
InChI keySVMPQLHYWRTQCX-DBHVCDLJSA-M
InChI1S/C18H15BrN5O6PS.Na/c19-17-21-11-14(24(17)16-12(25)13-10(29-16)7-28-31(27,32)30-13)22-18-20-9(6-23(18)15(11)26)8-4-2-1-3-5-8;/h1-6,10,12-13,16,25H,7H2,(H,20,2
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥98% (HPLC)

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