RO5256390

RO5256390

Stock Code: 3575512
Manufacturer Part No: SML1893-25MG
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£681.11 (exc VAT) per 25MG
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Biochem/physiol Actions


RO5256390 is an agonist of Trace amine-associated receptor 1 (TAAR1), a GPCR primarily found in the brain, expressed in areas where the major monoamine amine transmitters (DA and NE) are also present. RO5256390 is a selective TAAR1 agonist shown to be a negative regulator of dopamine transmission. It has antipsychotic activity in models of schizophrenia, reduces cocaine′s reinforcng effects, and blocks binge-eating disorder.

Colourwhite to beige
Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
SolubilityDMSO: 10 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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