RINVANIL

RINVANIL

Stock Code: 3575136
Manufacturer Part No: SML1600-5MG
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£124.94 (exc VAT) per 5MG
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Biochem/physiol Actions


TRPV1 (transient receptor potential vanilloid 1) is a capsaicin receptor. It is strongly expressed in sensory neurons and participates in pain perception. In brain, it regulates neuronal function, motor behaviour and neuroinflammation. Capsaicin plays an important role in the activation of TRPV1.


Rinvanil is a Capsaicin analogue that potently activates transient receptor potential vanilloid 1 (TRPV1) channels. Rinvanil induces neuroprotective mild hypothermia in ischemic brain injured mice through TRPV1 activation. Rinvanil exhibits potent anticancer activity in cancer cell lines including cervical (HeLa, CaSKi, ViBo) and leukemia (P388, J774, WEHI-3) cell lines. Rinvanil is not cytotoxic to normal lymphocytes.

Colourcolorless to yellow
Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
Formoil
Assay≥98% (HPLC)

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