R-KETOROLAC

R-KETOROLAC

Stock Code: 3575222
Manufacturer Part No: SML1654-5MG
Order Now for 7 day delivery
£320.36 (exc VAT) per 5MG
Quantity: - +

Biochem/physiol Actions


Ketorolac ((rac)-5-benzoyl-1,2-3H-pyrrolo[1,2a] pyrrole1-carboxylic acid) is a non-steroidal anti-inflammatory drug (NSAID). It is used as a racemic mixture that contains a 1:1 ratio of the R(+) and S(?) stereoisomers. It is broadly used off-label as a parenteral analgesic in children. Ketorolac serves as a non-narcotic analgesic. It prevents the synthesis of prostaglandins, peripheral to the central nervous system.


R-Ketorolac is potent and selective Rho-family GTPases Cdc42 (cell division control protein 42) and Rac1 (Ras-related C3 botulinum toxin substrate 1) allosteric inhibitor that modulates downstream GTPase-dependent physiologic responses critical to tumor metastasis. R-ketorolac significantly inhibits ovarian cancer cell adhesion, migration, and invasion.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyOZWKMVRBQXNZKK-LLVKDONJSA-N
InChI1S/C15H13NO3/c17-14(10-4-2-1-3-5-10)13-7-6-12-11(15(18)19)8-9-16(12)13/h1-7,11H,8-9H2,(H,18,19)/t11-/m1/s1
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥95% (HPLC)

There are no downloads for this product.