PR-619, >=95% (HPLC)

PR-619, >=95% (HPLC)

Stock Code: 3574087
Manufacturer Part No: SML0430-5MG
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£405.32 (exc VAT) per 5MG
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Application


PR-619 has been used:as a component of lysis buffer and also as a deubiquitinase inhibitor to treat proteins derived from SILAC-labeled Jurkat cellsas a pan-deubiquitinase inhibitor to study its effect on adenoassociated virus (AAV) transductionin radioimmunoprecipitation assay buffer (RIPA) buffer used for ubiquitination assays


Biochem/physiol Actions


PR-619 is a cell permeable broad spectrum deubiquitylating enzymes (DBUs) inhibitor. PR-619 induces the accumulation of polyubiquitylated proteins in cells without directly affecting proteasome activity.


Packaging


1, 5 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyZXOBLNBVNROVLC-UHFFFAOYSA-N
InChI1S/C7H5N5S2/c8-2-13-4-1-5(14-3-9)7(11)12-6(4)10/h1H,(H4,10,11,12)
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: 5 mg/mL (clear solution)
Formpowder
Assay≥95% (HPLC)

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