PKF118-310, >=98% (HPLC), powder

PKF118-310, >=98% (HPLC), powder

Stock Code: 3573435
Manufacturer Part No: K4394-25MG
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£747.96 (exc VAT) per 25MG
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Biochem/physiol Actions


PKF118-310 is an antagonist of the Tcf4/b-catenin signaling. The compound disrupts the Tcf4/b-catenin complex and inhibits expression of Tcf4 responsive genes. PKF118-310 inhibits expression of survivin and induces apoptosis in HCC, colon tumor and lymphocytic leukemia cell lines.


Packaging


5, 25 mg in glass bottle

Colourwhite to light brown
Quality Level100
InChI keySLGRAIAQIAUZAQ-UHFFFAOYSA-N
InChI1S/C7H7N5O2/c1-11-6(13)4-5(10-7(11)14)12(2)9-3-8-4/h3H,1-2H3
ManufacturerSIGMA-ALDRICH
SolubilityH2O: 10 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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