Pitstop 2

Pitstop 2

Stock Code: 3574557
Manufacturer Part No: SML1169-25MG
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£611.46 (exc VAT) per 25MG
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Application


Pitstop 2 has been used as an inhibitor of clathrin-mediated endocytosis.


Biochem/physiol Actions


Pitstop 2 is a selective inhibitor of clathrin-mediated endocytosis.


Pitstop 2 also has an ability to breakdown the nuclear pore complex (NPC) permeability barrier and decrease importin ? binding along with alteration of the NPC ultrastructure. Pitstop 2 is also involved in the inhibition of platelet activation, platelet aggregation and secretion.


Pitstop 2 is a selective inhibitor of clathrin-mediated endocytosis that acts via blocking ligand access to the clathrin terminal domain. Pitstop 2 selectively inhibits clathrin-mediated HIV entry and stalls clathrin-coated pit (CCP) dynamics.


Packaging


5, 25 mg in glass bottle

Colourwhite to light brown
Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
SolubilityDMSO: 20 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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