PHA-408

PHA-408

Stock Code: 3573669
Manufacturer Part No: PZ0266-25MG
Order Now for 7 day delivery
£419.25 (exc VAT) per 25MG
Quantity: - +

Biochem/physiol Actions


PHA-408 is a potent, selective I kappa B-kinase 2 (IKK-2) inhibitor. PHA-408 is a tight binding, ATP competitive IKK-2 inhibitor with greater than 350-fold selectivity for IKK-2 vs IKK-1 (IC50 values of 10-40 nM at IKK-2 vs 14 µM at IKK-1). PHA-408 was shown to suppress inflammatory cellular events, and to reduce inflammation in animal models of arthritis.


Legal Information


Pfizer is a registered trademark of Pfizer, Inc.


Sold for research purposes under agreement from Pfizer Inc.


Other Notes


This compound was developed by Pfizer for Kinase Phosphatase Biology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: 5 mg/mL, clear (warmed)
Formpowder
Assay≥98% (HPLC)

There are no downloads for this product.