PF-06869206

PF-06869206

Stock Code: 3573856
Manufacturer Part No: PZ0389-25MG
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£498.64 (exc VAT) per 25MG
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Application


PF-06869206 has been used to selectively inhibit the activity of sodium-phosphate cotransporter 2a (NaPi2a).


Biochem/physiol Actions


PF-06869206 is a selective inhibitor against sodium-phosphate cotransporter 2A (NaPi-2a, NaPi-Iia, Na+/Pi cotransporter 2A, Na+-dependent phosphate cotransporter 2A).


PF-06869206 may be used to treat patients with mineral and hormonal derangements linked with increased cardiovascular risk in chronic kidney disease. This drug might also improve urinary phosphate excretion. PF-06869206 has an ability to decrease phosphate uptake in human embryonic kidney (HEK) cells transfected with mouse or rat renal sodium-dependent phosphate transporter genes (Npt2a).


Legal Information


Pfizer is a registered trademark of Pfizer, Inc.


Sold for research purposes under agreement from Pfizer Inc

Colourwhite to beige
ManufacturerSIGMA-ALDRICH
Storage Temp.room temp
SolubilityDMSO: 2 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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