Oz Biosciences OVA Antigen mRNA Modified N1-Methyl-Pseudouridine

Stock Code: 3075050
Manufacturer Part No: MRNA40-20

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Descriptions

OVA mRNAs have been designed to produce high expression level of Ovalbumin protein. OVA mRNA encodes for OVA protein, a commonly used antigen for immunisation and biochemical studies and also an established model allergen for airway hyper-responsiveness. OZ Biosciences mRNAs are produced by in vitro transcription. mRNAs are stabilised at the 5' end by modified nucleotides capping (Cap1) and contain a poly(A) tail at the 3' end. Sequences have been optimised to yield improved stability and performance.

Ready-to-use stabilised OVA mRNA

Concentration: 1.0mg/mL in 1mM sodium citrate, pH 6.4.

mRNA length: 1375nt. MW MRNA42 = 445528g/mol; MRNA41 = 451168g/mol; MRNA40 = 448348g/mol

MRNA42 does not bear any additional nucleotide modifications

MRNA41 is modified with 5-methoxyuridine (5moU) to reduce innate immune responses

MRNA40 is modified with N1-methyl-pseudouridine (N1-mψ) to reduce innate immune response