OTX015

OTX015

Stock Code: 3575145
Manufacturer Part No: SML1605-5MG
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£355.18 (exc VAT) per 5MG
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Biochem/physiol Actions


OTX015 is a potent inhibitor of the BET bromodomain proteins 2, 3, and 4 (BRD2/3/4).


It binds to bromodomain and extra-terminal domain (BET) proteins and inhibits their binding to the chromatin. This in turn prevents gene transcription. OTX015 has been shown to inhibit proliferation of cells in haematological malignancies.


Packaging


5, 25 mg in glass bottle

Colourwhite to light brown
Quality Level100
InChI keyGNMUEVRJHCWKTO-FQEVSTJZSA-N
InChI1S/C25H22ClN5O2S/c1-13-14(2)34-25-22(13)23(16-4-6-17(26)7-5-16)28-20(24-30-29-15(3)31(24)25)12-21(33)27-18-8-10-19(32)11-9-18/h4-11,20,32H,12H2,1-3H3,(H,27,33)
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥98% (HPLC)

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