NSC130813

NSC130813

Stock Code: 3574250
Manufacturer Part No: SML0922-25MG
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£552.96 (exc VAT) per 25MG
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Biochem/physiol Actions


NSC130813 blocks protein-protein interactions between XPF and ERCC1, two proteins involved in nucleotide excision repair (NER). The compound, NSC130813, blocks repair of DNA damage induced by platinum-based ctyotoxic drugs and DNA alkylating agents. NSC130813 synergistically potentiates cell death in cancer cell lines treated with cisplatin or mitomycin C.


Other Notes


air sensitive


Packaging


5, 25 mg in glass bottle

Colouryellow to orange
Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
SolubilityH2O: 10 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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