NIMORAZOLE

NIMORAZOLE

Stock Code: 3575578
Manufacturer Part No: SML1935-50MG
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£151.82 (exc VAT) per 50MG
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Biochem/physiol Actions


Nimorazole is a nitroimidazole-based hypoxic cell-radiation sensitizer with less toxicity than etanidazole or misonidazole. Under low oxygen (hypoxic) condition, reductive activation of its 5-nitroimidazole moiety leads to enhanced adduct formation with reduced glutathione, which form the basis of cancer/tumour-selective radiation sensitization. Nimorazole is also a known anti-infective agent against trichomoniasis, an infectious disease caused by the protozoan parasite Trichomonas vaginalis.

Colourwhite to beige
Quality Level100
InChI keyMDJFHRLTPRPZLY-UHFFFAOYSA-N
InChI1S/C9H14N4O3/c14-13(15)9-7-10-8-12(9)2-1-11-3-5-16-6-4-11/h7-8H,1-6H2
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
SolubilityDMSO: 30 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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