NILVADIPINE

NILVADIPINE

Stock Code: 3574275
Manufacturer Part No: SML0945-10MG
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£67.28 (exc VAT) per 10MG
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Biochem/physiol Actions


Nilvadipine is a potent calcium channel blocker that is used for treatment of hypertension. Nilvadipine, as other dihydropyridine calcium antagonists, decreases intracellular calcium concentration causing dilation of the coronary and systemic arteries. Nilvadipine acutely reduced brain Aβ levels in a transgenic mouse model of Alzheimer′s disease (AD).


Nilvadipine, apart from its antihypertensive effect, is known to decrease the accumulation of ?-amyloid protein in the brain. Therefore, it is effective in the treatment of Alzheimer’;s disease. Nilvadipine also promotes cognitive function in hypertensive patients.


General description


Nilvadipine is a dihydropyridine drug.


Packaging


10, 50 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyFAIIFDPAEUKBEP-UHFFFAOYSA-N
InChI1S/C19H19N3O6/c1-10(2)28-19(24)15-11(3)21-14(9-20)17(18(23)27-4)16(15)12-6-5-7-13(8-12)22(25)26/h5-8,10,16,21H,1-4H3
ManufacturerSIGMA-ALDRICH
Storage Temp.room temp
SolubilityDMSO: 15 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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