NELARABINE

NELARABINE

Stock Code: 3575325
Manufacturer Part No: SML1736-50MG
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£536.25 (exc VAT) per 50MG
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Biochem/physiol Actions


Nelarabine is an antineoplastic purine nucleoside analog used in T-cell acute lymphoblastic leukemia. It is a pro-drug of Ara-G, which is converted by cellular kinases to the active 5′-triphosphate, Ara-GTP. Incorporation of Ara-GTP into DNA leads to inhibition of DNA synthesis and apoptosis.


Packaging


10, 50 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyIXOXBSCIXZEQEQ-KBNQYOMWSA-N
InChI1S/C11H15N5O5/c1-20-9-5-8(14-11(12)15-9)16(3-13-5)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14,15)/t4-,6-,7+,10?/m1/s1
ManufacturerSIGMA-ALDRICH
SolubilityH2O: 5 mg/mL, clear (warmed)
Formpowder
Assay≥98% (HPLC)

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