MoTP, >=98% (HPLC)

MoTP, >=98% (HPLC)

Stock Code: 3573999
Manufacturer Part No: SML0047-25MG
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£490.29 (exc VAT) per 25MG
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Application


MoTP may be used in cell signaling and differentiation studies.


Biochem/physiol Actions


MoTP (also known as 33N14) reversibly blocks the specification of neural crest cells into melanocytes in zebrafish studies. Differentiation of neural crest cell-derived melanoblasts proceeds to late developmental stages, but they fail to reach the terminal stage of melanin production and die. Melanocytotoxicity is dependent on tyrosinase activity which convert it into a toxic form. MoTP specifically ablates only cells that express tyrosinase at high levels, which in the embryo are limited to melanoblasts and newly formed melanocytes. MoTP should be a useful tool for elucidating melanocyte stem cell regeneration, recruitment, and maintenance.


Packaging


5, 25 mg in glass bottle

Colourwhite to tan
Quality Level100
InChI keyYHKNLUTUXZDOQI-UHFFFAOYSA-N
InChI1S/C14H21NO2S/c16-13-3-5-14(6-4-13)18-12-2-1-7-15-8-10-17-11-9-15/h3-6,16H,1-2,7-12H2
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: ≥80 mg/mL
Formpowder
Assay≥98% (HPLC)

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