MONNA

MONNA

Stock Code: 3574222
Manufacturer Part No: SML0902-5MG
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£153.21 (exc VAT) per 5MG
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Biochem/physiol Actions


MONNA is a TMEM16A (ANO1) calcium-activated chloride channel blocker. MONNA blocks rhTMEM16A (ANO1) channel currents in HEK293 cells with and IC50 of 1.27 µM. The compound MONNA does not affect related human or mouse chloride channels bestrophin-1, CLC2 and CFTR at concentrations up to 10 µM.


MONNA (benzbromarone (Benzb) and N-((4-methoxy)-2-naphthyl)-5-nitroanthranilic acid) is a TMEM16A antagonists. It affects the liberation of sarcoplasmic reticulum (SR) calcium in human airway smooth muscle cells.


Packaging


5, 25 mg in glass bottle

Colourlight orange to dark orange
Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
SolubilityDMSO: 20 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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