ML240

ML240

Stock Code: 3574429
Manufacturer Part No: SML1071-5MG
Order Now for 7 day delivery
£168.54 (exc VAT) per 5MG
Quantity: - +

Application


ML240 has been used as an inhibitor of D2 ATPase activity of valosin-containing protein.


Biochem/physiol Actions


ML240 is a selective, ATP-competetive inhibitor of AAA ATPase p97, also called valosine containing protein (VCP). The IC50 for p97 inhibition is 110 nM. ML240 rapidly induces activity of Caspases 3 and 7, leading to apoptosis. ML240 has potent antiproliferative activity towards NCI-60 cancer cell lines.


Packaging


5, 25 mg in glass bottle

Colour, white to yellow to light brown
Quality Level100
InChI keyNHAMBLRUUJAFOY-UHFFFAOYSA-N
InChI1S/C23H20N6O/c1-30-19-13-7-10-16-20(19)27-23(28-21(16)25-14-15-8-3-2-4-9-15)29-18-12-6-5-11-17(18)26-22(29)24/h2-13H,14H2,1H3,(H2,24,26)(H,25,27,28)
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: 5 mg/mL, clear (warmed)
Formpowder
Assay≥98% (HPLC)

There are no downloads for this product.