MK6-83

MK6-83

Stock Code: 3575007
Manufacturer Part No: SML1509-5MG
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£115.47 (exc VAT) per 5MG
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Biochem/physiol Actions


MK6-83 is a potent activator of wild type and mutant variants F465L and F408D of TRPML1 channel. MK6-83 weakly activates TRPML mutants R403C or V446L. MK6-83 restores channel function and rescue disease associated abnormalities in mucolipidosis type IV (MLIV) patient cells.


MK6-83is known to stimulate caspase-3-dependent apoptosis. It can also decrease the viability of cells.


Packaging


5, 25 mg in glass bottle

Colourwhite to brown
Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
SolubilityDMSO: 5 mg/mL, clear (warmed)
Formpowder
Assay≥98% (HPLC)

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