LORLATINIB

LORLATINIB

Stock Code: 3573568
Manufacturer Part No: PZ0039-5MG
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£126.33 (exc VAT) per 5MG
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Biochem/physiol Actions


Lorlatinib (PF-06463922) is a potent, selective brain-penetrable inhibitor of both anaplastic lymphoma kinase (ALK) and c-ros Oncogene 1 (ROS1) with strong activity against most known ALK and ROS1 mutants identified in patients with crizotinib-resistant disease. It is in clinical trials for the treatment of non–small cell lung cancer (NSCLC).


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Pfizer is a registered trademark of Pfizer, Inc.


Sold for research purposes under agreement from Pfizer Inc.

Colourwhite to beige
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: 2 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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