Lomitapide

Lomitapide

Stock Code: 3574840
Manufacturer Part No: SML1385-5MG
Order Now for 5 day delivery
£179.68 (exc VAT) per 5MG
Quantity: - +

Application


Lomitapide has been used as a microsomal triglyceride transfer protein (MTP) inhibitor to study its effects on very-low-density lipoproteins (VLDL) export in mouse hepatocytes.


Biochem/physiol Actions


Lomitapide is an inhibitor of microsomal triglyceride transfer protein (MTP). Lomitapide has been shown to be highly effective in reducing LDL-cholesterol and triglycerides, and has been aproved for treatment of homozygous familial hypercholesterolemia.


Lomitapide can lower the secretion of very-low-density lipoproteins (VLDL) and chylomicrons.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyMBBCVAKAJPKAKM-UHFFFAOYSA-N
InChI1S/C39H37F6N3O2/c40-38(41,42)25-46-36(50)37(33-13-5-3-10-30(33)31-11-4-6-14-34(31)37)21-7-8-22-48-23-19-28(20-24-48)47-35(49)32-12-2-1-9-29(32)26-15-17-27(18-1
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
SolubilityDMSO: 20 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

There are no downloads for this product.