LIXIVAPTAN

LIXIVAPTAN

Stock Code: 3574102
Manufacturer Part No: SML0603-5MG
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£113.80 (exc VAT) per 5MG
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Biochem/physiol Actions


Arginine vasopressin (AVP) plays an important part in circulatory and water homoeostasis and is important in renal hemodynamic alterations, water retention, and cardiac remodeling in congestive heart failure (CHF). Lixivaptan is an AVP V2-receptor selective antagonist that increases water excretion and normalizes serum sodium levels. Lixivaptan has been in clinical trials for hyponatremia associated with heart failure.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyPPHTXRNHTVLQED-UHFFFAOYSA-N
InChI1S/C27H21ClFN3O2/c1-17-8-9-19(29)13-23(17)26(33)30-20-10-11-22(24(28)14-20)27(34)32-16-21-6-4-12-31(21)15-18-5-2-3-7-25(18)32/h2-14H,15-16H2,1H3,(H,30,33)
ManufacturerSIGMA-ALDRICH
Further Info4% w/w in ethyl acetate
SolubilityDMSO: 20 mg/mL, clear
Formpowder
Assay≥96% (HPLC)

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