LDK1305

LDK1305

Stock Code: 3576534
Manufacturer Part No: SML2582-25MG
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£486.11 (exc VAT) per 25MG
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Biochem/physiol Actions


LDK1305 is a selective positive allosteric modulator of CB1 that promote the binding of the agonist CP55940 and inhibits binding of orthosteric inverse agonist SR141716A. LDK1305 is a beta-arrestin-biased ligand that induces cellular internalization of the receptor and recruitment of β-arrestin 2 in HEK293 cells. It stimulates also β-arrestin 1-dependent phosphorylation of the downstream kinases, ERK1/2, MEK, and Src.

Colourwhite to beige
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
SolubilityDMSO: 2 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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