INDY

Stock Code: 3574355
Manufacturer Part No: SML1011-25MG
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£385.82 (exc VAT) per 25MG
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Biochem/physiol Actions


INDY is a potent inhibitor of Dyrk1A and Dyrk1B (dual-specificity tyrosine-phosphorylation-regulated kinase 1). The IC50 values for inhibition of Dyrk1A and 1B are 240 and 230 nM, respectively. INDY impairs the self-renewal capacity of neural stem cells and glioblastoma tumor-initiating cells.

Colourwhite to beige
Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
SolubilityDMSO: 5 mg/mL, clear (warmed)
Formpowder
Assay≥98% (HPLC)

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