IMM-01

IMM-01

Stock Code: 3574418
Manufacturer Part No: SML1064-5MG
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£150.43 (exc VAT) per 5MG
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Application


IMM-01 has been used as a formin activator to study its effects on motor neurons (MNs).


Biochem/physiol Actions


IMM-01 binds and activates formin thereby leading to autoinhinition.


IMM-01 is an agonist of the mammalian Diaphanous (mDia)-related formins that triggers actin assembly and microtubule stabilization, serum response factor-mediated gene expression, cell-cycle arrest, and apoptosis. IMM-01 inhibits DID–DAD binding, which in turn activates mDia family of formins in cells. IMM-01 slows tumor growth in a mouse xenograft model of colon cancer.


Packaging


5, 25 mg in glass bottle

Colourwhite to light brown
Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
SolubilityDMSO: 10 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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