HTS01037

HTS01037

Stock Code: 3576222
Manufacturer Part No: SML2374-25MG
Order Now for 7 day delivery
£360.05 (exc VAT) per 25MG
Quantity: - +

Biochem/physiol Actions


HTS01037 is a selective, high-affinity fatty acid-binding protein FABP4 (AFABP; aP2) antagonist (aP2 Ki = 0.67 µM; EFABP/HF/IFABP/LFABP Ki = 3.40/9.07/6.57/8.17 µM) that targets aP2 long-chain fatty acid-binding site. HTS01037 is shown to downregulate basal and fatty acid-stimulated LTC4 levels in primary murine peritoneal macrophages (0.2-20 µM), upregulate murine macrophage RAW 264.7 intracellular free fatty acids and uncoupling protein 2 (UCP2) mRNA levels (30 µM), as well as suppress PPARγ target genes expression in IL-4 polarized human primary macrophages (10-25 µM).

Colourwhite to beige
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
SolubilityDMSO: 2 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

There are no downloads for this product.