GSK690

GSK690

Stock Code: 3576289
Manufacturer Part No: SML2419-25MG
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£360.05 (exc VAT) per 25MG
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Biochem/physiol Actions


GSK690 (GSK354) is a cell-permeable pyrrolidinylmethoxypyridine-based compound that inhibits lysine-specific demethylase 1 (LSD1; KDM1A) in a potent and reversible manner (IC50= 90 nM) without affecting MAO-A activity (IC50>200 μM). GSK690 is shown to induce the expressions of CD86 (EC50= 1.4 μM in THP1 cells) and LY96 (EC50= 423 nM in MV4-11 cells), and prevent adipogenesis in murine preadipocyte cultures.

Colourwhite to beige
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
SolubilityDMSO: 2 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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