GNF 5837

Stock Code: 3574164
Manufacturer Part No: SML0844-5MG

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£174.11 (exc VAT) per 5MG

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Sale of Professional Pesticide Products

You are reminded of the following legal requirements relating to the purchase and use of professional pesticides.

As from 26th November 2015 it is an offence for anyone to purchase pesticides authorised for professional use unless they have ensured that the intended end user holds the relevant specified certificate(s).
(Section 9 (5), The Plant Protection Products (Sustainable Use) Regulations 2012)

and

Pesticides approved for professional use must only be used by users holding the relevant specified certificate(s).
(Section 8 (1), The Plant Protection Products (Sustainable Use) Regulations 2012) (Part III of the Food and Environment Protection Act 1985, and related Codes of Practice).

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Descriptions

Biochem/physiol Actions

GNF-5837 is an orally bioavailable Trk inhibitor (IC₅₀ = 8 and 12 nM for TrkA and TrkB, respectively). GNF-5837 inhibits growth of Ba/F3 cells expressing Tel-Trl fusions. IC₅₀ values for growth inhibition are Tel-TrkA = 11 nM, Tel-TrkB = 9 nM and Tel-TrkC = 7 nM.

Features and Benefits

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

5, 25 mg in glass bottle

Specifications

Colour	yellow to orange
Quality Level	100
Manufacturer	SIGMA-ALDRICH
Storage Temp.	2-8°C
Solubility	DMSO: 5 mg/mL, clear (warmed)
Form	powder
Assay	≥98% (HPLC)

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SHA 68
KYOTORPHIN ACETATE SALT
PRACTOLOL
NHI-2
ABH HYDROCHLORIDE
ASP7663
DIENOGEST
ULIPRISTAL ACETATE
OXICONAZOLE NITRATE
THIOCOLCHICOSIDE
OPHIOBOLIN A
ALCLOMETASONE DIPROPIONATE
OGERIN
OGERIN NEGATIVE CONTROL
SW033291
METAMIZOLE SODIUM HYDRATE
FICZ
PEMETREXED DISODIUM HEPTAHYDRATE
GW501516
UMI-77
SUPROFEN
PYRAZOFURIN
APCIN
TEGASEROD MALEATE
AZD1480 HPLC
KY-05009
CRT0066101 HYDROCHLORIDE
C-DIM12
MK6-83
SR9238
SR1848
SIRREAL2
ANLE138B
DS-437
SID 3712249
MACELIGNAN
ESTETROL
(+)-JQ1
(-)-JQ1
ABIRATERONE ACETATE
ILOPERIDONE
ERDOSTEINE
SB-334867
TREPROSTINIL
CINACIGUAT HYDROCHLORIDE
MARINOPYRROLE A
I-BRD9
NMDI14 97% (HPLC)
TDFA TRIFLUOROACETATE
SBI-0206965
SITAMAQUINE TOSYLATE
APRATASTAT
CLARAMINE TRIFLUOROACETATE SALT
SCR7 PYRAZINE
RN-9893
THPN
ZIBOTENTAN
GV-58
TIPIRACIL HYDROCHLORIDE
MS049 HYDROCHLORIDE
S3QEL 2
MS023 HYDROCHLORIDE
AEM1
YODA1
FURAMIDINE DIHYDROCHLORIDE
AZORAMIDE
LP-211
BAY-678
A-196
MCB-613
ACOTIAMIDE DIHYDROCHLORIDE
ARGLABIN
GENTIOPICROSIDE
TOLRESTAT
CYCLOSPORIN H
UNDECYLPRODIGIOSIN HYDROCHLORIDE
RUBROFUSARIN
AFTIN-4
Moxifloxacin Hydrochloride 98% (HPLC)
ROSEOFLAVIN
ORITAVANCIN DIPHOSPHATE
CILENGITIDE TRIFLUOROACETIC ACID SALT
LULICONAZOLE
VR23
RINVANIL
RQ-00203078
BAY-598
NDB
OTX015
LESINURAD
BESIFLOXACIN HYDROCHLORIDE >=98% HPLC
DAPIPRAZOLE HYDROCHLORIDE
LAFUTIDINE
2-PMPA
RP-?8-?BR-?CGMPS SODIUM SALT
SEN177
ICA-069673
GSK2033
GARENOXACIN MESYLATE MONOHYDRATE
TAZAROTENIC ACID
NGI-1
OSMI-1
JNJ-63533054
GEMIFLOXACIN MESYLATE
DFHBI
BRASSININ
PIPECURONIUM BROMIDE
HEXAMINOLEVULINATE HYDROCHLORIDE
VX-745
BRD3308
DC_AC50
WWL70
DHED
AS2444697
MRT68921 DIHYDROCHLORIDE
EPIBLASTIN A
24(S)-Hydroxycholesterol
UROLITHIN B
ILOPROST
RGFP966
R-KETOROLAC
BI-9564
CBR-5884
GEFITINIB
GSK484
NCT-503
ARFORMOTEROL TARTRATE
TIPIFARNIB
NCX 4016
NCT-503 INACTIVE CONTROL
JT010
UPCDC30245
TAROCIN A1
DEL-22379
EX26
ENDOSIDIN2
CDN1163
GSK2850163
RIBOCIL-C
NEOSEPTIN-3
3BDO
KT172
EUPATILIN
ZM323881 HYDROCHLORIDE
TVB-3166
RSV604
OGG1 INHIBITOR O8
(R)-ZINC-3573 >=98% HPLC
BX430
TEMOPORFIN
JNJ-47965567
K6PC-5
TALNIFLUMATE
TNCA
CARPROFEN
DCAI
VEDAPROFEN
LUF5834
RTC13
MSAB
FINDY
PFM01
NELARABINE
beraprost sodium
FIN56
TH1020
ETAKG
A-971432
RAPTINAL
JNJ-55511118
CD1530
BAM15
SI-2
DIPHYLLIN
SPARSTOLONIN B
XIMELAGATRAN
PHIKAN083 HYDROCHLORIDE
GIVINOSTAT HYDROCHLORIDE HYDRATE
BAY-876
PROPACETAMOL HYDROCHLORIDE
SR0987
PDD00017273
CENTHAQUIN
SINENSETIN
PRIMA-1MET
Tariquidar 98%
UROLITHIN A
TENOFOVIR DISOPROXIL FUMARATE
TENOFOVIR
ATAZANAVIR
10-CL-BBQ
JK-2
YU142670
SB-258719
PPTN TRIFLUOROACEATE SALT >=98% HPLC
BIQ
IMR-1
ANI9
BCI-121
PIRODAVIR
AKEBIA SAPONIN D
CCF642
EMD-87580
JJKK-048
DDR1 INHIBITOR 7RH
ML385
BETA-ODAP
K-604
KURARINONE
EPI-001
RI(DL)-2
KAEMPFERITRIN
BANOXANTRONE DIHYDROCHLORIDE
AZD5438
LRE1
AZD2461
J104129 FUMARATE
TP-472
OUL35
RBIN-2
KIN1408
NVS-PAK1-1
BRUSATOL
DELAFLOXACIN
KIN1400
(2R6R)-HYDROXYNORKETAMINE HYDROCHLORIDE
DM-NOFD
(2S6S)-HYDROXYNORKETAMINE HYDROCHLORIDE
TADALAFIL
SPL-334
RS 67333 HYDROCHLORIDE
AR231453
MITOGLITAZONE
VPC-13566
RO5256390
VH298
IGURATIMOD
SR144528
SOBETIROME
ML348
ISAM-140
AS1517499
ESI-05
SYROSINGOPINE
INI-43
GSK461364A
ASB14780
TUG-891
T-26C
ML349
NEXINHIB20
ML364
NVP-ADW742
K67
A-395 HYDROCHLOLRIDE
BEPRISTAT 2A HYDROCHLORIDE
GAT211
UM-164 TRIFLUOROACETATE
CORM-401
A-1210477
DR4004 HYDROCHLORIDE
NIMORAZOLE
RO 64-6198
SN-6
LY450139
SCH 79797 DIHYDROCHLORIDE
ADDA 5 HYDROCHLORIDE
CGP3466B MALEATE
DROTAVERINE HYDROCHLORIDE
BZ-423
AM-9074
S1QEL1.1
SYNTA66
UVI3003
GAT229
GDC-0879
X-34
CICLESONIDE
FIIN-4
BAY 60-6583
GA3-AM
GSK583
EF5 98% HPLC
ABIRATERONE D4A METABOLITE
PKUMDL-WQ-2201
LINOLEAMIDE
PKUMDL-WQ-2101
LLY-284
LLY-283
NVP-AEW541
UCB35625
DIM-C-PPHCO2ME
J113863 CIS ISOMER
FM-381
NIBR189
PSB-603
GSK6853
TASIN-1 HYDROCHLORIDE
GW806742X
PS432
FM-479
BOP
CAPZIMIN DIMER
S3226
KLH45
SM4
GSK621
CANGRELOR TETRASODIUM SALT
SMART-420
TIOTROPIUM BROMIDE HYDRATE
CICLOPIROX
CINACALCET HYDROCHLORIDE
RU 24969 HEMISUCCINATE
DERACOXIB
MM11253
COMPOUND C108
GSK4027
DS44170716
ATRASENTAN HYDROCHLORIDE
MIND4-17
UCSF924
UCSF924NC
GSK4028
AH-7614
GA11
TASIMELTEON
S4
AGN 193109
DIDOX
GIGANTOL
SR2595
RO3280
SAK3
CE3F4
27-HYDROXYCHOLESTEROL
DMAT
R-IMPP HYDROCHLORIDE
ARM390
AR-R17779 HYDROCHLORIDE
AZ3451
LY2109761
LCAT ACTIVATOR COMPOUND A
LALISTAT 2
SEA0400
ZD0947
BEVIRIMAT
5;7-DIHYDROXYTRYPTAMINE HYDROBROMIDE
ST1926
DAVUNETIDE TRIFLUOROACETATE SALT
LBQ657
MEQUITAZINE
SR9011
LURASIDONE HYDROCHLORIDE
23-HYDROXYBETULINIC ACID
OX03050
(R)-9BMS
FX1
GIMERACIL
ONO-AE3-208
ALISKIREN HEMIFUMARATE
ATN-161
AZD1283
[ALA13]-APELIN-13 TRIFLUOROACETATE
[PYR1]-APELIN-13 TRIFLUOROACETATE
SJ000291942
PROCAINAMIDE HYDROCHLORIDE
NCT-501
NAMI-A
DALCETRAPIB
R115866
BIBO 3304 TRIFLUOROACETATE SALT
LYS05
KINK-1 HYDROCHLORIDE
NIBR-0213
RIPA-56
FOSAMPRENAVIR CALCIUM
GSK256066
AMBRISENTAN
ROFLUPRAM
TULATHROMYCIN A
ST034307
FR194921
ZD7155 HYDROCHLORIDE
HA15
A-33
ELND006
NED-K
DYNAPYRAZOLE-A
BRAZILIN
RO 65-6570 HYDROCHLORIDE
FINAFLOXACIN
BIOTINYL TYRAMIDE
IR415
MDL-860
TCS 401
SOLIFENACIN SUCCINATE
SILODOSIN
AILANTHONE
TB5
TD52
SR-18292 MALEATE
S-EQUOL
SULFO-N-SUCCINIMIDYL OLEATE SODIUM
AZ6102
MBX2546
TAM1 HYDROCHLORIDE
DELTARASIN TRIHYDROCHLORIDE
TAK-901
ERLOTINIB HYDROCHLORIDE
HOMOPLANTAGININ
MINODRONIC ACID MONOHYDRATE
R-568 HYDROCHLORIDE
STA-21
TELITHROMYCIN
HPN-07
BEPRISTAT 1A
KML29
TAK-475
DIPHENIDOL HYDROCHLORIDE
HX531
NS3861
MS012
S 38093-2
LDC000067 HYDROCHLORIDE
KEA1-97
SA4503
LY2955303
KEVETRIN HYDROCHLORIDE
PA-6
POLOPPIN
RL5A
BRD5529
SNS-314 MESYLATE
AZD6482
ZOTAROLIMUS
SAJM589
L-F001
OCTYL-(R)-2HG
SGC-GAK-1
SGC-GAK-1N
OCTYL-?-KG
SKA-121
SR-4995
BRD6989
AUBIPYOME
RWJ 67657
CPI-637
BI01383298
APREPITANT
TAKINIB
PARECOXIB SODIUM
SNS-032
SGC-AAK1-1
SGC-AAK1-1N
CU-CPT9A
WAY-267464 DIHYDROCHLORIDE
MS436
RO5263397
BC-LI-0186
EMRICASAN
FOSAPREPITANT DIMEGLUMINE
NUCIFERINE
ERASIN
(a)-SPINASTEROL
XMU-MP-1 HYDROCHLORIDE
1S;3R-RSL 3
CL075
L-012 SODIUM SALT
ORMELOXIFENE
NAV-2729
INF39
IU1-47
FTBMT
BTSA1
AC1903
1G244
SK-216
LSN3154567
Nanchangmycin
TP053
J-113397
BI-2545
D3-(b)ARR
IBR2
LAPATINIB
TASPOGLUTIDE TRIFLUOROACETATE SALT
CONIVAPTAN HYDROCHLORIDE
RAMELTEON
LADOSTIGIL TARTRATE
COL003
GEA-69
MICAFUNGIN SODIUM
LY404039
FRAX486
ADX-47273
AZD-2098
KUNB31
DDR1-IN-1
TH-257
A192621
NDT9513727
VU0155069
BAY 60-2770
EVEROLIMUS
LENALIDOMIDE
MITO A IODIDE
BIIL260 HYDROCHLORIDE
POSACONAZOLE
ANIDULAFUNGIN
HBT1
ANI-7
S119-8
CCG-100602
NSC61610
DIMETHYOXY-ETOMIDATE
GSK180736A
CHLORFLAVONIN
PHENDC3
PHOTOREGULIN3
EPOY
VILDAGLIPTIN
TOSEDOSTAT
BPK-29
CTEP
LODOXAMIDE
ATAZANAVIR SULFATE
BAY 60-7550
HIGENAMINE HYDROCHLORIDE
CELGOSIVIR
ORNIPRESSIN ACETATE SALT
ILAPRAZOLE
GSK1702934A
NLX-112 HYDROCHLORIDE
BAY-6035
MSC1094308
BD064
CEAPIN-A7
PEROSPIRONE HYDROCHLORIDE
DYNARRESTIN
VU0463271
IACS-9571 TRIFLUOROACEATE
SK052-145-2
DIASARONE-I
4-OCTYL ITACONATE
SGC3027N
SGC3027
SJB3-019A
RHYNCHOPHYLLINE
RU.521
BAY-707
BAY-604
FERROQUINE
DABIGATRAN ETEXILATE
ARAMCHOL
GPR39-C3
HMR-1556
BIX02189
A939572
ISAVUCONAZOLE
D-NMAPPD
LX-4
KINESORE
WRR139
AST487
PHENPROCOUMON
(Z)-ENDOXIFEN
TIPELUKAST
DABIGATRAN
FC-99 HYDROCHLORIDE
?-MURICHOLIC ACID
HTS01037
KDU691
GSK963
GSK962
DALBAVANCIN
FLUORIZOLINE
APY29
SC75741
ISOSILYBIN
BAY 87-2243
SW157765
AP39
JNS 1-40
DREADD AGONIST 21 DIHYDROCHLORIDE
XL019
AT9283
ELOCALCITOL
alpha-DHED
DOOKU1
SR16832
ML327
IMEGLIMIN HYDROCHLORIDE
WYC-209
EC23
JI130
UNC3866 TRIFLUOROACETATE SALT
NITD008
ABC99
KPR-2579
EU1794-4
EU1794-27
HET0016
PS10
GSK690
SOPHOCARPINE
TERLIPRESSIN ACETATE SALT
MANIDIPINE HYDROCHLORIDE
BIBN4096BS
VU0134992 HYDROCHLORIDE
ETHYL ROSMARINATE
TP-238 HYDROCHLORIDE
BAY-958 HYDROCHLORIDE
H-151
MAGNOLIN
SGC-IMLLT
MS417
GLPG0974
BAY 41-4109
PKS21004
TC-A2317 HYDROCHLORIDE
TPA023
PK4C9
THIQ
BIIE 0246 HYDROCHLORIDE
LY2444296
GSK-A1
Q151
MEPB
AMGEN16
M090
SK33
LM22B-10
HZ-166
KRN2
CY-09
OXFBD04
CINPA1
OXANTHROQUINONE G01
GYY4137 SODIUM, DICHLOROMETHANE-FREE
UPGL00004
PITAVASTATIN CALCIUM
HS56
LARAZOTIDE ACETATE
MIRABEGRON
TICAGRELOR
FESOTERODINE FUMARATE
AZD3839
MARBOFLOXACIN
PERAMIVIR TRIHYDRATE
CABAZITAXEL
TASQUINIMOD
APC366 TRIFLUOROACETATE
AZASETRON HYDROCHLORIDE
ENGELETIN
VX-702
PRALATREXATE
MLS1082
D-I03
VATALANIB DIHYDROCHLORIDE
TY-52156
SENICAPOC
MF-094
MF-095
PELLITORINE
LAQUINIMOD
REGADENOSON
ANAMORELIN
MI-503
BRD6929
DIPROVOCIM-1
PRAMLINTIDE ACETATE
FEXINIDAZOLE
TAFLUPROST
SW063058
K-TMZ
MDL-800
TH5487
JEDI2
JEDI1
DJ-V-159
MRK-740
MRK-740-NC
NSAH
KL-2
NAB-14
KA-11
NSC49652
GLX351322
KCC-07
MS094
MS645
AZ32
AP-C5
RIPK2 INHIBITOR 1
BIO-0919278 RACEMATE
PT-TTPY
AMINOPYRIDINE 2
N-ARACHIDONYLGLYCINE
C-176
OB-1
ML162
RAPHIN1
PIAA
MLS6585
CL097
LY2784544
XMD8-87
JH-II-127
NSC 146109 HYDROCHLORIDE
CPHPC
AZM475271
MITOCDNB
GSHTRACER
NERAMEXANE HYDROCHLORIDE
PIXANTRONE DIMALEATE
A-769662
TAFLUPROST ACID
GNE-140
LDK1305
AQ1 TRIFLUOROACETIC ACID SALT
JNJ0966
AZD3463
SCH-39166 HYDROBROMIDE
ARTEETHER
MS0021570
SAPACITABINE
AZD1208
SPHYNOLACTONE-7
ETRAVIRINE
ATACIGUAT
MELITRACEN HYDROCHLORIDE
DTAG-13
CW3388
GNE-9278
BAY-885
51164
BRAGSIN2
CLEVIDIPINE BUTYRATE
CSRM617 HYDROCHLORIDE
JH-I-25
SESELIN
BOBCAT339
SECNIDAZOLE
CARBOPROST TROMETHAMINE
BEPOTASTINE BESILATE
CELIPROLOL HYDROCHLORIDE
FRAX1036
BROMONOSCAPINE
ZT-12-037-01
ABC1183
(+)-JQ-1 CARBOXYLIC ACID
NVP-BSK805 TRIHYDROCHLORIDE
IITZ-01
AUTOPHINIB
QX77
Z944 HYDROCHLORIDE
SB4
NPD8733
XIE62-1004
BDT001
YZ129
METHENAMINE HIPPURATE
S29434
ML365
NCGC00135472
CX614
CA3
LOMIBUVIR
ELESCLOMOL
PERETINOIN
SORAFENIB
REPARIXIN
TSQ
MP-A08
SPASTAZOLINE
SPA70
SELAMECTIN
GNF-4877
AGN194310
DIFLAPOLIN
AC261066
ITK7
BAY-8002
CEVIPABULIN FUMARATE
TANDUTINIB HYDROCHLORIDE
DEFERASIROX
KI20227
PFF-1
ES24
CRIPGBM
RIPGBM
DBET6
DTRIM24
THAL-SNS-032
DBET1
J30-8
PYRIDOSTATIN HYDROCHLORIDE
DCPIB
FB23
RSM932A
DFHBI-1T
EVT-101 DIHYROCHLORIDE
SHMT INHIBITOR HIT 1
DRAINH-A250
CBA
ZCZ011
ES9-17
VU0155072
PITOLISANT HYDROCHLORIDE
AMG517
GSK503
NVS-ZP7-4
ENDOSIDIN9
NPBA
AER-271
SITAFLOXACIN SESQUIHYDRATE
SRS11-92
IFSP1
NETUPITANT
DAPAGLIFLOZIN PROPANEDIOL MONOHYDRATE
PLP (139-151) DEPALMITOYLATED (HU BO M
JMJD2A ACTIVE HUMAN
IDH2 FLAG-TAG
PD-L1 (CD274) FC FUSIONMOUSE
IL-17RA FC FUSION BIOTIN-LABELED
IL-17A
ENTEROKINASEHUMAN
RELAXIN-3HUMAN
THROMBINACTIVEBOVINE PLASMA(HIGHACTIVI
THROMBINACTIVEHUMAN PLASMA
Tocainide hydrochloride, >=98% (HPLC), solid
Topiramate, >=98% (HPLC), solid
Taurine, >=99%
TPCA-1, >=95% (HPLC), powder
TBBz, >=98% (HPLC), powder
Tolvaptan, >=98% (HPLC), powder
TFLLR-NH2 trifluoroacetate salt, , >98% (HPLC)
Picropodophyllotoxin, >=96% (HPLC), powder
URB597, >=98% (HPLC), powder
UCN-01, >=97% (HPLC), powder
UCL 2077, >=98% (HPLC), solid
Venlafaxine hydrochloride, >=98% (HPLC), powder