Fumonisin B2 from Fusarium moniliforme, sphingosine N-acyltransferase inhibitor

Fumonisin B2 from Fusarium moniliforme, sphingosine N-acyltransferase inhibitor

Stock Code: 3577774
Manufacturer Part No: F3771-10MG
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Application


Fumonisin B2 (FB2) from Fusarium moniliforme has been used:as a standard for the detection of FB2 by high performance liquid chromatography (HPLC) in corn based food productsused as standard in the determination of fumonisin B1 and B2 in corn and corn-based products by high-performance liquid chromatographyas a standard in the determination of mycotoxins by HPLC


Biochem/physiol Actions


Inhibitor of sphingosine N-acyltransferase. Blocks the formation of ceramide from sphingosine.


General description


Mycotoxin originally isolated from Fusarium sp, which grows on corn. Produces neural tube defects and craniofacial abnormalities in fetuses. Many strains of Aspergillus niger growing naturally on grapes are capable of producing fumonisin B2, so it is now a concern for human consumption of grapes, raisins, and wine.


Fumonisin B2 (FB2) is a diester of tricarballylic acid and polyhydric alcohols.. Fumonisins B2 (FB2) does not have one or more hydroxyl groups at the C5 or C10 positions.


Packaging


1 mg in glass bottle


10 mg in glass insert

Quality Level100
InChI keyUXDPXZQHTDAXOZ-UHFFFAOYSA-N
InChI1S/C34H59NO14/c1-5-6-12-21(3)32(49-31(43)18-24(34(46)47)16-29(40)41)27(48-30(42)17-23(33(44)45)15-28(38)39)14-20(2)11-9-7-8-10-13-25(36)19-26(37)22(4)35/h20-27
ManufacturerSIGMA-ALDRICH
Solubilitymethanol: 10 mg/mL, clear, colorless to faintly yellow
Formpowder
Assay≥96% (TLC)

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