FICZ

FICZ

Stock Code: 3574979
Manufacturer Part No: SML1489-5MG
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£582.21 (exc VAT) per 5MG
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Biochem/physiol Actions


FICZ (6-formylindolo(3,2b)carbazole) being a photooxidation product of tryptophan, might serve as a chemical messenger of light.


FICZ is a potent high affinity ligand of the aryl hydrocarbon receptor (AhR), which is a ligand-activated transcription factor that activates the expression of aromatic hydrocarbon metabolizing enzyme genes such as the CYP1A1 gene and has also been shown to have multiple additional roles in cell-cycle regulation, development and maturation of many tissues, control of inflammation, and immune response. FICZ is a photoproduct of tryptophan and is believed to be an endogenous AhR ligand. It is extremely potent, with a Kd value of 0.07 nM.


Packaging


1, 5 mg in glass bottle

Colouryellow
Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
SolubilityDMSO: 0.5 mg/mL, clear (warmed)
Formlyophilized powder
Assay≥95% (HPLC)

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