FH1

FH1

Stock Code: 3574141
Manufacturer Part No: SML0826-25MG
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£346.82 (exc VAT) per 25MG
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Biochem/physiol Actions


FH1 (BRD-K4477) was found to enhance hepatocyte functions and promote the differentiation of induced pluripotent stem cell–derived hepatocytes toward a more mature phenotype than what had previouslybeen obtainable. Human induced pluripotent stem (iPS) cells that are differentiated toward hepatocyte-like (iHep) cells typically show an immature hepatic phenotype and have limited use as a renewable source of functional human hepatocytes. Cultures treated with both FH1 (BRD-K4477) and another compound that induces proliferation, FPH1 (BRD-6125), contained larger colonies of iHep cells, which showed more pronounced hepatocyte morphologies with a more mature phenotype than previously obtainable.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyOEXMNSOPAKOPEF-UHFFFAOYSA-N
InChI1S/C17H18N2O2/c1-12(20)18-16-7-3-14(4-8-16)11-15-5-9-17(10-6-15)19-13(2)21/h3-10H,11H2,1-2H3,(H,18,20)(H,19,21)
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
SolubilityDMSO: 10 mg/mL, clear (warmed)
Formpowder
Assay≥98% (HPLC)

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