Fetuin from fetal bovine serum, lyophilized powder, BioReagent, suitable for cell culture

Stock Code: 3571663
Manufacturer Part No: F3385-25G
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Application


Fetuin from fetal bovine serum has been used:as a substrate to determine neuraminidase activityto validate the specificity of sialidasesto stabilize m-calpain


Biochem/physiol Actions


Fetuin acts as an inhibitor of insulin receptor tyrosine kinase. It modulates bone remodeling and calcium metabolism. Fetuin regulates vascular calcification, insulin resistance, protease activity control, keratinocytes migration and breast tumor cell proliferative signaling. It functions as a biomarker for neurodegenerative diseases. Fetuin exhibits anti-inflammatory property.


General description


Fetuin from fetal bovine serum is a plasma glycoprotein. It is a 64 kDa glycoprotein, which is produced by the liver and adipose tissue.A glycoprotein derived from FBS that is used as Fetuin has been used at a concentration of 500 mg/ml to supplement serum free F12 medium (along with insulin, transferrin and 2-mercaptoethanol) in culture of embryonal carcinoma cells.


Packaging


100 mg in poly bottle


1, 5, 25 g in poly bottle


Preparation Note


Prepared by ammonium sulfate fractionation of fetal bovine serum by the method of Pederson, K.O., J. Phys. and Colloid Chem., 51, 164 (1947).

Quality Level200
Pack25G
ManufacturerSIGMA-ALDRICH
Technique(s)cell culture - mammalian: suitable
Product LineBioReagent
Storage Temp.2-8°C
Impurities≤0.3% free N-acetylneuraminic acid
SolubilityH2O: 1 mg/mL
Formlyophilized powder

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