ESTETROL

ESTETROL

Stock Code: 3575025
Manufacturer Part No: SML1523-25MG
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£1,005.64 (exc VAT) per 25MG
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Biochem/physiol Actions


Estetrol (E4, 15α-Hydroxyestriol) is an estrogen steroid hormone produced exclusively during pregnancy by the fetal liver. Estetrol is a selective estrogen receptor modulator (SERM) with potent estrogenic effects on vaginal mucosa, bone and brain, neutral effect on liver, and anti-estrogen effects on breast tissue. Estetrol has higher affinity for ERα over ERβ. Estetrol is being studied for its potential as a contraceptive, a drug for meopausal symptoms, and an anticancer agent.


General description


Estetrol is an estrogenic steroid molecule produced exclusively during pregnancy by the fetal liver.


Packaging


5, 25 mg in glass bottle

Quality Level100
InChI keyAJIPIJNNOJSSQC-NYLIRDPKSA-N
InChI1S/C18H24O4/c1-18-7-6-12-11-5-3-10(19)8-9(11)2-4-13(12)14(18)15(20)16(21)17(18)22/h3,5,8,12-17,19-22H,2,4,6-7H2,1H3/t12-,13-,14-,15-,16-,17+,18+/m1/s1
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
SolubilityDMSO: 20 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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